B7-H6 Protein (AA 25-262) (hIgG-His-tag)
Aperçu rapide pour B7-H6 Protein (AA 25-262) (hIgG-His-tag) (ABIN7677905)
Antigène
Voir toutes B7-H6 (NCR3LG1) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 25-262
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Purification/Conjugué
- Cette B7-H6 protéine est marqué à la hIgG-His-tag.
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Séquence
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DLKVEMMAGG TQITPLNDNV TIFCNIFYSQ PLNITSMGIT WFWKSLTFDK EVKVFEFFGD HQEAFRPGAI VSPWRLKSGD ASLRLPGIQL EEAGEYRCEV VVTPLKAQGT VQLEVVASPA SRLLLDQVGM KENEDKYMCE SSGFYPEAIN ITWEKQTQKF PHPIEISEDV ITGPTIKNMD GTFNVTSCLK LNSSQEDPGT VYQCVVRHAS LHTPLRSNFT LTAARHSLSE TEKTDNFS
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Purification
- > 95% by SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA with Human NCR3. The ED50 range ≤500 ng/ml.
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Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (Biotin,His-Avi Tag)
NCR3LG1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) protein (His tag)NCR3LG1 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (His tag)NCR3LG1 Origine: Humain Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, ELISA, WB, AcA, Imm Active
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-259) protein (His tag)NCR3LG1 Origine: Cynomolgus Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (His tag,AVI tag,Biotin)NCR3LG1 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1) (AA 25-262) (Active) protein (Fc Tag,AVI tag,Biotin)NCR3LG1 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
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Autre désignation
- B7-H6
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Sujet
- B7-H6, also known as NCR3LG1, is a member of the B7 family of immune co-stimulatory proteins. B7-H6 is as a cell-surface ligand for the NKp30-activating receptor expressed on natural killer cells. It is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells, and is consistent with the detection of NKp30 binding sites on many tumors. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis. Recombinant human B7-H6, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
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Poids moléculaire
- 53.6kDa (477aa)
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NCBI Accession
- NP_001189368
Antigène
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