Cathepsin Z Protein (CTSZ) (AA 24-303) (His tag)

N° du produit ABIN7596248

Cette protéine Recombinant Cathepsin Z est exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour Cathepsin Z Protein (CTSZ) (AA 24-303) (His tag) (ABIN7596248)

Antigène: Cathepsin Z (CTSZ)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS), Enzyme Activity Assay (EAA)

Pureté: > 95 %

Détail du produit

Attributs du protein: AA 24-303

Purification/Conjugué: Cette Cathepsin Z protéine est marqué à la His tag.

Séquence: GLYFRRGQTC YRPLRGDGLA PLGRSTYPRP HEYLSPADLP KSWDWRNVDG VNYASITRNQ HIPQYCGSCW AHASTSAMAD RINIKRKGAW PSTLLSVQNV IDCGNAGSCE GGNDLSVWDY AHQHGIPDET CNNYQAKDQE CDKFNQCGTC NEFKECHAIR NYTLWRVGDY GSLSGREKMM AEIYANGPIS CGIMATERLA NYTGGIYAEY QDTTYINHVV SVAGWGISDG TEYWIVRNSW GEPWGERGWL RIVTSTYKDG KGARYNLAIE EHCTFGDPIV LEHHHHHH

Purification: > 95% by SDS-PAGE

niveau d'endotoxine: < 1 EU per 1ug of protein (determined by LAL method)

Biological Activity Comment: Specific activity is > 1,400pmol/min/ug in which one unit will convert 1.0pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Cathepsin Z (CTSZ)

Autre désignation: Cathepsin Z

Sujet: Cathepsin Z, also known Cathepsin X and Cathepsin P, is a member of the C1 family of lysosomal cysteine proteases. It exhibits carboxy-monopeptidase and carboxy-dipeptidase activity. This protein regulates maturation of dendritic cells and plays important role in the initiation of adaptive immunity. It is also involved in tumor and immune cells as higher expression is found in tumour and immune cells of prostate and gastric carcinomas and inmacrophages of gastric mucosa. Recombinant human Cathepsin Z protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 32.5 kDa (288aa)

NCBI Accession: NP_001327

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones