Betacellulin Protein (BTC) (AA 32-118)
Aperçu rapide pour Betacellulin Protein (BTC) (AA 32-118) (ABIN7827936)
Antigène
Voir toutes Betacellulin (BTC) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 32-118
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Fonction
- Human Betacellulin Protein
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Séquence
- Asp32-Gln118
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Attributs du produit
- Recombinant Human Betacellulin Protein is expressed from E.coli without tag.It contains Asp32-Gln118.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 0.1 EU per μg by the LAL method.
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Biological Activity Comment
- Human Betacellulin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50-for this effect is 0.10-1.50 ng/ml (QC Test).,The purity of Human Betacellulin is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- Betacellulin (BTC)
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Autre désignation
- Betacellulin
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Sujet
- Betacellulin (BTC) belongs to the epidermal growth factor (EGF) family of peptide ligands that are characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family.
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Poids moléculaire
- 9.76 kDa. The protein migrates to 14-18 kDa based on Bis-Tris PAGE result.
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UniProt
- P35070
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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