Leptin Protein (LEP)

N° du produit ABIN7849713

Protéine Recombinant Leptin exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour Leptin Protein (LEP) (ABIN7849713)

Antigène: Leptin (LEP)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: >95 % by SDS-PAGE

Détail du produit

Fonction: Recombinant Human Leptin Protein

Stérilité: 0.2 μm filtered

niveau d'endotoxine: <1 EU/μg by LAL test

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl,50 mM NaCl,10 % Trehalose,0.02 %Tween80, pH 8.5.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Détail du antigène

Antigène: Leptin (LEP)

Autre désignation: Leptin

Sujet:

Synonyms: LEP, LEPD, OB, OBS, leptin

Description: Recombinant human leptin is produced by the E.coli system, with the target gene encoding Val22-Cys167 expressed.

Background: Leptin, also known as obese protein,is a protein hormone predominantly made by adipocytes (cells of adipose tissue). Its primary role is likely to regulate long-term energy balance.As one of the major signals of energy status, leptin levels influence appetite, satiety, and motivated behaviors oriented toward the maintenance of energy reserves (e.g., feeding, foraging behaviors).The amount of circulating leptin correlates with the amount of energy reserves, mainly triglycerides stored in adipose tissue. High leptin levels are interpreted by the brain that energy reserves are high, whereas low leptin levels indicate that energy reserves are low, in the process adapting the organism to starvation through a variety of metabolic, endocrine, neurobiochemical, and behavioral changes.

UniProt: P41159

Pathways: Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process