DLL1 Protein (AA 18-723)

N° du produit ABIN7866014

Protéine Recombinant DLL1 exprimée dans CHO Cells.

Aperçu rapide pour DLL1 Protein (AA 18-723) (ABIN7866014)

Antigène: DLL1 (delta-Like 1 (DLL1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: CHO Cells

Pureté: >95 % , as determined by SDS-PAGE and HPLC

Détail du produit

Attributs du protein: AA 18-723

Fonction: Human DLL1 Protein Recombinant

Séquence: SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF

Attributs du produit:

Protein Size: Recombinant DLL1 migrates as an approximately 57 kDa protein due to glycosylation under reducing conditions in SDS-PAGE.

Sequence Position: Optimized DNA sequence encoding Human DLL1 mature chain including a C-terminal 6xHis tag was expressed in CHO. Recombinant Human Delta-like protein 1 encodes amino acid residues 18-723.

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg(1EU/μg).

Biological Activity Comment: DLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 μg/ml

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Buffer: DLL1 was Lyophilized from PBS, pH 7.2.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this product can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Date de péremption: 24 months

Détail du antigène

Antigène: DLL1 (delta-Like 1 (DLL1))

Autre désignation: DLL1

Poids moléculaire: 57 kDa

Pathways: Signalisation Notch, Stem Cell Maintenance