FGF23 Protéine

N° du produit ABIN7937380

Protéine Recombinant FGF23 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour FGF23 Protéine (ABIN7937380)

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % by SDS-PAGE and HPLC analyses.

Détail du produit

Fonction: Recombinant Human Fibroblast Growth Factor 23

Séquence: YPNASPLLGS SWGGLIHLYT ATARNSYHLQ IHKNGHVDGA PHQTIYSALM IRSEDAGFVV ITGVMSRRYL CMDFRGNIFG SHYFDPENCR FQHQTLENGY DVYHSPQYHF LVSLGRAKRA FLPGMNPPPY SQFLSRRNEI PLIHFNTPIP RRHTRSAEDD SERDPLNVLK PRARMTPAPA SCSQELPSAE DNSPMASDPL GVVRGGRVNT HAGGTGPEGC RPFAKFI

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 1 EU/ug of rHuFGF-23 as determined by LAL method.

Biological Activity Comment: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2.0 x10³ IU/mg in the presence of 0.3 μg/ml of rMuKlotho and 10 μg/ml of heparin.

Information d'application

Commentaires:

Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Date de péremption: 12 months

Détail du antigène

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Autre désignation: Fibroblast Growth Factor 23

Poids moléculaire: 25.3 kDa

ID gène: 8074

UniProt: Q9GZV9

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion