EPH Receptor B4 Protein (EPHB4) (AA 561-987)

N° du produit ABIN7938807

Cette protéine Recombinant EPH Receptor B4 est produite dans Baculovirus infected Insect Cells.

Aperçu rapide pour EPH Receptor B4 Protein (EPHB4) (AA 561-987) (ABIN7938807)

Antigène: EPH Receptor B4 (EPHB4)

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: Screening Assay (ScA), Functional Studies (Func), Activity Assay (AcA)

Détail du produit

Attributs du protein: AA 561-987

Fonction: Recombinant EPHB4 (561-987) protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Recombinant EPHB4 (561-987) protein is supplied in 25 mM HEPESNaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100 and 0.5 mM TCEP.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Détail du antigène

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EPHB4

Sujet:

Protein Background: EPHB4(Ephrin type-B receptor 4) is a Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/ functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.

Short Description: Recombinant EPHB4 (561-987) protein that includes amino acids 561-987 of human EPHB4 protein (accession number NP_004435.3) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 48.89 kDa.

Aliases: Ephrin type-B receptor 4, TYRO11, HTK, MYK1, Tyrosine-Protein Kinase Receptor HTK

Pathways: Signalisation RTK