ERBB3 Protein (AA 665-1342)
Aperçu rapide pour ERBB3 Protein (AA 665-1342) (ABIN7939510)
Antigène
Voir toutes ERBB3 ProtéinesType de proteíne
Origine
Source
Application
-
-
Attributs du protein
- AA 665-1342
-
Fonction
- Recombinant ErbB3 / HER3 (665-1342) protein
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Recombinant ErbB3 / HER3 (665-1342) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
Stock
- -80 °C
-
Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
-
Autre désignation
- ErbB3 & HER3
-
Sujet
-
Protein Background: ErbB3 (Receptor tyrosine-protein kinase erbB-3) is a tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.
Short Description: Recombinant ErbB3 / HER3 (665-1342) protein that includes amino acids 665-1342 of human ErbB3 protein (accession number NP_001973.2) was expressed in a baculovirus expression system and contains an N-terminal FLAG tag. The molecular weight of the protein is 76.52 kDa.
Aliases: Receptor tyrosine protein kinase erbB-3, HER3, Oncogene Homolog 3, LCCS2, FERLK, LCCS2, FERLK, ErbB-3, ErbB3-S, EC 2.7.10
-
Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
-