RPS6KA1 Protéine
Aperçu rapide pour RPS6KA1 Protéine (ABIN7939514)
Antigène
Voir toutes RPS6KA1 ProtéinesType de proteíne
Origine
Source
Application
-
-
Fonction
- Recombinant RPS6KA1/RSK1 protein
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !ProduitSystème d'expressionConjuguéOriginPrix à partir deSystème d'expression HEK-293 CellsConjugué His tagOrigin HumanPrix à partir de 11.737,02 €Système d'expression Cell-free protein synthesis (CFPS)Conjugué Strep TagOrigin HumanPrix à partir de 15.754,29 €Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-724) protein (His tag)
custom-made RPS6KA1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-735) protein (His tag)custom-made RPS6KA1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (AA 1-735) protein (GST tag)RPS6KA1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RPS6KA1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Recombinant RPS6KA1 / RSK1 protein is supplied in 25 mM HEPES NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
Stock
- -80 °C
-
Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
-
Autre désignation
- RPS6KA1 & RSK1
-
Sujet
-
Protein Background: RPS6KA1 - (Ribosomal Protein S6 Kinase A1) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77. This protein regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. Diseases associated with RPS6KA1 include Coffin-Lowry Syndrome and Tuberous Sclerosis.
Short Description: Recombinant RPS6KA1 / RSK1 protein was expressed in baculovirus expression system as the full length protein (accession number NP_002944.2) with a N-terminal FLAG tag. The molecular weight of the protein is 84 kDa.
Aliases: Ribosomal Protein S6 Kinase A1
-
Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
-
