Prothrombin Protéine

N° du produit ABIN934835

Cette protéine Native Prothrombin est produite dans Human.

Aperçu rapide pour Prothrombin Protéine (ABIN934835)

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Type de proteíne: Native

Activité biologique: Active

Origine: Humain

Source: Human

Pureté: > 98 % pure

Détail du produit

Attributs du produit: Purified native Human Prothrombin protein
Bioactivity: 9.7 units/mg protein - One unit of activity is equivalent to the Prothrombin activity in one milliliter of human normal plasma.
Protein Source: Human serum/plasma

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).

Précaution d'utilisation: Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C.

Détail du antigène

Antigène: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Autre désignation: Prothrombin

Sujet: Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes.
Description: Human serum/plasma.

Poids moléculaire: 72 kDa

Pathways: Système du Complément, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling