HSP27 Protéine

N° du produit ABIN934933

Détail du produit

Antigène: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Séquence: MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD ETAAK

Attributs du produit: Purified recombinant Human Hsp27 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Pureté: > 95 % pure

niveau d'endotoxine: < 1.0 EU per µg of protein (determined by LAL method)

Information d'application

Indications d'application: Hsp27 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Hepes, pH 7.5, containing 0 mM DTT, and 100 mM KCl.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Autre désignation: Hsp27 (HSPB1 Produits)

Synonymes: CMT2F Protein, HMN2B Protein, HS.76067 Protein, HSP27 Protein, HSP28 Protein, Hsp25 Protein, SRP27 Protein, 27kDa Protein, Hsp27 Protein, cb153 Protein, cb660 Protein, hsp1 Protein, hsp25 Protein, hsp27 Protein, id:ibd2821 Protein, sb:cb660 Protein, zgc:103437 Protein, HSPB1 Protein, cmt2f Protein, hs.76067 Protein, hsp28 Protein, heat shock protein family B (small) member 1 Protein, heat shock protein 1 Protein, heat shock protein, alpha-crystallin-related, 1 Protein, heat shock protein family B (small) member 1 L homeolog Protein, HSPB1 Protein, Hspb1 Protein, hspb1 Protein, hspb1.L Protein

Sujet: Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Recombinant human Hsp27 was overexpressed in E. coli and purified by conventional chromatography.
Alternative Names: Growth-related 25 kDa protein protein, CMT2F protein, Hsp27, Heat shock 27 kDa protein protein, Heat Shock Protein 27 protein, Hsp 28 protein, HspB1 protein, HSP 27 protein, Hsp28 protein, P25 protein, Stress responsive protein 27., DKFZp586P1322 protein, Heat shock 27kDa protein 1 protein, Estrogen regulated 24 kDa protein protein, HS.76067 protein, Hsp27 protein, Heat shock 27 kDa protein 28 kDa heat shock protein protein, Hsp-27 protein, Hsp25 protein, Hsp 27, at shock 25kDa protein 1 protein, Heat shock protein beta-1 protein, Hsp-27, Hspb1 protein, Hsp B1 protein, Hsp27 protein, Heat shock 28kDa protein 1 protein, Heat shock protein beta 1 protein, HspB1 protein, HSP25 protein, SRP27 protein, Heat Shock Protein27 protein, Hsp 27 protein

Poids moléculaire: 22.7 kDa (205 AA)

Pathways: Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling