Leptin Protein (LEP)
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- Antigène Voir toutes Leptin (LEP) Protéines
- Leptin (LEP)
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Séquence
- MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
- Attributs du produit
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Purified recombinant Mouse Leptin protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Pureté
- > 95 % pure
- Top Product
- Discover our top product LEP Protéine
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- Indications d'application
- Leptin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in PBS, pH 7.4.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- RT/-20 °C
- Stockage commentaire
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Antigène
- Leptin (LEP)
- Autre désignation
- Leptin (LEP Produits)
- Synonymes
- ob Protein, obese Protein, LEPD Protein, OB Protein, OBS Protein, leptin Protein, Lep Protein, LEP Protein, lep Protein
- Sujet
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Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: Obese protein protein, Obesity factor protein, LEP protein, OB protein, , Leptin Mouse protein, Leptin protein, OBS protein - Poids moléculaire
- 16 kDa (147 AA)
- Pathways
- Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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