ENO2/NSE Protein (AA 1-434)
Aperçu rapide pour ENO2/NSE Protein (AA 1-434) (ABIN934970)
Antigène
Voir toutes ENO2/NSE (ENO2) ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 1-434
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Séquence
- MSIEKIWARE ILDSRGNPTV EVDLYTAKGL FRAAVPSGAS TGIYEALELR DGDKQRYLGK GVLKAVDHIN STIAPALISS GLSVVEQEKL DNLMLELDGT ENKSKFGANA ILGVSLAVCK AGAAERELPL YRHIAQLAGN SDLILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAESFRD AMRLGAEVYH TLKGVIKDKY GKDATNVGDE GGFAPNILEN SEALELVKEA IDKAGYTEKI VIGMDVAASE FYRDGKYDLD FKSPTDPSRY ITGDQLGALY QDFVRDYPVV SIEDPFDQDD WAAWSKFTAN VGIQIVGDDL TVTNPKRIER AVEEKACNCL LLKVNQIGSV TEAIQACKLA QENGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL MRIEEELGDE ARFAGHNFRN PSVL
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Attributs du produit
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Purified recombinant Human NSE protein
Expression System: E.coli
Bioactivity: Specific activity: > 8 units/mL. One unit will convert 1.0 m of 2-phosphoglycerate to phospho(enol)pyruvate per minute at pH 7.5 at 25C
Molecular weight on SDS-PAGE will appear higher. -
niveau d'endotoxine
- < 1.0 EU per µg of protein (determined by LAL method)
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Indications d'application
- NSE protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris, pH 7.5, containing 0.1 M KCl, and 5 mM MgSO4.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))
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Autre désignation
- NSE
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Sujet
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Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. Recombinant NSE was expressed in E. coli and purified by conventional chromatography techniques.
Alternative Names: ENO2 protein, Enolase 2 gamma neuronal protein, neuronal) protein, Neuron specific enolase protein, Neuron specific gamma enolase protein, NSE protein, Gamma enolase protein, 2 phospho D glycerate hydrolyase protein, ENOG protein, Neuron-Specific Enolase protein, Eno 2 protein, Neurone specific enolase., Enolase 2 (gamma protein, Neural enolase protein, Enolase2 protein -
Poids moléculaire
- 47 kDa ( 434 AA)
Antigène
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