TANK Protein (AA 1-119)

N° du produit ABIN935032

Protéine Recombinant TANK exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour TANK Protein (AA 1-119) (ABIN935032)

Antigène: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 % pure

Détail du produit

Attributs du protein: AA 1-119

Séquence: MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI

Attributs du produit: Purified recombinant Human TANK protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Information d'application

Indications d'application: TANK protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: TANK (TRAF Family Member-Associated NFKB Activator (TANK))

Autre désignation: TANK

Sujet: TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TRAF interacting protein TANK isoform b protein, TRAF interacting protein protein, TRAF family member associated NFKB activator protein, TRAF2 protein, I-TRAF protein, TRAF interacting protein TANK isoform a, ITRAF protein, TRAF family member associated NF KAPPA B activator protein, TRAF interacting protein TANK isoform b I TRAF protein

Poids moléculaire: 13.6 kDa (119 AA)

Pathways: Signalisation p53, Signalisation TLR, Activation of Innate immune Response