ATF3 Protein (AA 1-181)

N° du produit ABIN935110

Protéine Recombinant ATF3 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour ATF3 Protein (AA 1-181) (ABIN935110)

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 % pure

Détail du produit

Attributs du protein: AA 1-181

Séquence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

Attributs du produit: Purified recombinant ATF3 protein
Expression System: E.coli

Information d'application

Indications d'application: ATF3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 2 M Urea and 20 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: ATF3 (Activating Transcription Factor 3 (ATF3))

Autre désignation: ATF3

Sujet: ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Alternative Names: ATF 3, ATF-3 protein, ATF 3 protein, ATF3, ATF-3, Cyclic AMP dependent transcription factor ATF3 protein, ATF3deltaZip3 protein, ATF3deltaZip2 protein, cAMP dependent transcription factor ATF3 protein, ATF3deltaZip2c protein, Cyclic AMP-dependent transcription factor ATF-3 protein

Poids moléculaire: 20.6kDa (181 AA)

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response