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ATF3 Protein (AA 1-181)

ATF3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
N° du produit ABIN935110
  • Antigène Voir toutes ATF3 Protéines
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-181
    Origine
    • 6
    • 3
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Séquence
    MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
    Attributs du produit
    Purified recombinant ATF3 protein
    Expression System: E.coli
    Pureté
    > 90 % pure
    Top Product
    Discover our top product ATF3 Protéine
  • Indications d'application
    ATF3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 2 M Urea and 20 % glycerol.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    RT/-20 °C
    Stockage commentaire
    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Antigène
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Autre désignation
    ATF3 (ATF3 Produits)
    Synonymes
    zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
    Sujet
    ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
    Alternative Names: ATF 3, ATF-3 protein, ATF 3 protein, ATF3, ATF-3, Cyclic AMP dependent transcription factor ATF3 protein, ATF3deltaZip3 protein, ATF3deltaZip2 protein, cAMP dependent transcription factor ATF3 protein, ATF3deltaZip2c protein, Cyclic AMP-dependent transcription factor ATF-3 protein
    Poids moléculaire
    20.6kDa (181 AA)
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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