WISP2 Protéine

N° du produit ABIN935289

Détail du produit

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF

Attributs du produit: Purified recombinant Human CTGFL protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is between 10-20 ng/mL in the presence of 15 ng/mL of human IGF-II.

Pureté: > 95 % pure

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1- 1.0 mg/mL. Do not raise to neutral pH.

Buffer: Supplied lyophilized with no additives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Détail du antigène

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Autre désignation: CTGFL (WISP2 Produits)

Synonymes: MGC84196 Protein, WISP2 Protein, ccn5 Protein, CCN5 Protein, CT58 Protein, CTGF-L Protein, Ccn5 Protein, Crgr4 Protein, Ctgfl Protein, Rcop1 Protein, WNT1 inducible signaling pathway protein 2 Protein, WNT1 inducible signaling pathway protein 2 S homeolog Protein, WISP2 Protein, wisp2.S Protein, wisp2 Protein, Wisp2 Protein

Sujet: CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors.
Alternative Names: WISP2 protein, CCN5 protein, CT-58 protein, Connective Tissue Growth Factor-Like protein protein

Poids moléculaire: 24.3 kDa

Pathways: Signalisation WNT, Growth Factor Binding