WISP2 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes WISP2 Protéines
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette WISP2 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human WISP2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product WISP2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- Autre désignation
- Wisp2 (WISP2 Produits)
- Synonymes
- MGC84196 Protein, WISP2 Protein, ccn5 Protein, CCN5 Protein, CT58 Protein, CTGF-L Protein, Ccn5 Protein, Crgr4 Protein, Ctgfl Protein, Rcop1 Protein, WNT1 inducible signaling pathway protein 2 Protein, WNT1 inducible signaling pathway protein 2 S homeolog Protein, WISP2 Protein, wisp2.S Protein, wisp2 Protein, Wisp2 Protein
- Sujet
- This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
- Poids moléculaire
- 24.2 kDa
- NCBI Accession
- NP_003872
- Pathways
- Signalisation WNT, Growth Factor Binding
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