Cardiotrophin 1 Protein (CTF1)
Aperçu rapide pour Cardiotrophin 1 Protein (CTF1) (ABIN935297)
Antigène
Voir toutes Cardiotrophin 1 (CTF1) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LYGEWVSRTE GDLGQLVPGG VA
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Attributs du produit
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Purified recombinant Mouse Cardiotrophin 1 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of TF-1 cells was 1 x 10^6units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Cardiotrophin 1 (CTF1)
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Autre désignation
- Cardiotrophin 1
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Sujet
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CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations.
Alternative Names: Cardiotrophin-1, Cardiotrophin 1 protein, Cardiotrophin-1 protein, CT-1 protein, Cardiotrophin-1 protein, Cardiotrophin 1, Cardiotrophin 1 -
Poids moléculaire
- 21.3 kDa
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Pathways
- Signalistation JAK/STAT
Antigène
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