DLL4 Protéine

N° du produit ABIN935314

Protéine Recombinant DLL4 exprimée dans HEK-293T Cells.

Aperçu rapide pour DLL4 Protéine (ABIN935314)

Antigène: DLL4 (delta-Like 4 (DLL4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293T Cells

Pureté: > 95 % pure

Détail du produit

Séquence: SGVFQLQLQE FINERGVLAS GRPCEPGCRT FFRVCLKHFQ AVVSPGPCTF GTVSTPVLGT NSFAVRDDSS GGGRNPLQLP FNFTWPGTFS LIIEAWHAPG DDLRPEALPP DALISKIAIQ GSLAVGQNWL LDEQTSTLTR LRYSYRVICS DNYYGDNCSR LCKKRNDHFG HYVCQPDGNL SCLPGWTGEY CQQPICLSGC HEQNGYCSKP AECLCRPGWQ GRLCNECIPH NGCRHGTCST PWQCTCDEGW GGLFCDQDLN YCTHHSPCKN GATCSNSGQR SYTCTCRPGY TGVDCELELS ECDSNPCRNG GSCKDQEDGY HCLCPPGYYG LHCEHSTLSC ADSPCFNGGS CRERNQGANY ACECPPNFTG SNCEKKVDRC TSNPCANGGQ CLNRGPSRMC RCRPGFTGTY CELHVSDCAR NPCAHGGTCH DLENGLMCTC PAGFSGRRCE VRTSIDACAS SPCFNRATCY TDLSTDTFVC NCPYGFVGSR CEFPVGLP

Attributs du produit: Purified recombinant Human sDLL4 protein
Expression System: 293 cells
Bioactivity: The sDLL-4, when immobilized at concentrations >1.5 µg/mL will inhibit myogenesis in C2C12 cells.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: sDLL4

Sujet: Human sDLL4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. DLL4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL4 gene in mice resulted in severe vascular defects and death before birth.
Alternative Names: sDLL-4 protein, sDLL 4 protein, sDLL 4, sDLL4, sDLL-4 protein, Delta-like protein 4, Drosophila Delta homolog 4 protein, sDLL-4

Poids moléculaire: 54 kDa

Pathways: Signalisation Notch