DLL1 Protéine
Aperçu rapide pour DLL1 Protéine (ABIN935315)
Antigène
Voir toutes DLL1 ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF
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Attributs du produit
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Purified recombinant Human sDLL1 protein
Expression System: 293 cells
Bioactivity: Determined by the dose dependent growth suppression of the human acute mon °Cytic leukemia cell line, THP-1. sDLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 µg/mL. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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delta-Like 1 (DLL1) protein (Fc Tag)
DLL1 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
delta-Like 1 (DLL1) (AA 18-545) (Active) protein (Fc Tag)DLL1 Origine: Humain Hôte: CHO Cells Recombinant >90 % (SDS-PAGE) SDS Active
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from PBS, pH 7.5,.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- DLL1 (delta-Like 1 (DLL1))
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Autre désignation
- sDLL1
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Sujet
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Human sDLL-1 comprises the extracellular signaling domain of DLL1, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed in the heart and pancreas, and to a lesser extent in various other tissues. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors.
Alternative Names: sDLL-1 protein, Delta-like protein 1 protein, Delta-1 protein, sDLL1, sDLL 1 protein, sDLL 1, sDLL-1 protein, sDLL-1 -
Poids moléculaire
- 57-60 kDa
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Pathways
- Signalisation Notch, Stem Cell Maintenance
Antigène
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