Epigen Protéine

N° du produit ABIN935330

Cette protéine Recombinant Epigen est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Epigen Protéine (ABIN935330)

Antigène: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 98 % pure

Détail du produit

Séquence: AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA

Attributs du produit: Purified recombinant Human Epigen protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent stimulation of the proliferation of Mouse Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/mL.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Autre désignation: Epigen

Sujet: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
Alternative Names: EPG protein, Epithelial mitogen protein

Poids moléculaire: 7.9 kDa

Pathways: Signalisation RTK, EGFR Signaling Pathway