FGF23 Protéine
Aperçu rapide pour FGF23 Protéine (ABIN935370)
Antigène
Voir toutes FGF23 ProtéinesType de proteíne
Origine
Source
Pureté
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Séquence
- MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI
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Attributs du produit
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Purified recombinant Human FGF23 protein
Expression System: E.coli -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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Autre désignation
- FGF23
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Sujet
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The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF23, FGF21 and FGF19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
Alternative Names: FGF-23 protein, FGF-23, FGF23, FGF 23, Fibroblast Growth Factor-23 protein, FGF 23 protein, FGF-23 protein -
Poids moléculaire
- 22.5 kDa
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
Antigène
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