GZMB Protéine

N° du produit ABIN935398

Protéine Recombinant GZMB exprimée dans Baculovirus.

Aperçu rapide pour GZMB Protéine (ABIN935398)

Antigène: GZMB (Granzyme B (GZMB))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Baculovirus

Pureté: > 98 % pure

Détail du produit

Séquence: IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS

Attributs du produit: Purified recombinant Mouse Granzyme B protein
Expression System: Baculovirus
Bioactivity: Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity , when using the Ac-IEPD-pNA substrate at 250C, is greater than 750 nM/min per µg of enzyme.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant Mouse.

Poids moléculaire: 28.9 kDa

Pathways: Apoptose, Caspase Cascade in Apoptosis