IL-4 Protéine

N° du produit ABIN935533

Protéine Recombinant IL-4 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL-4 Protéine (ABIN935533)

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Escherichia coli (E. coli)

Pureté: > 98 % pure

Détail du produit

Séquence: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S

Attributs du produit: Purified recombinant Mouse IL4 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent proliferation of Mouse HT-2 cells is 5 x 10^5 units/mg.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.

Buffer: Supplied lyophilized with no additives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Autre désignation: IL4

Sujet: IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.
Alternative Names: Interleukin 4 protein, IL 4, IL 4 protein, IL-4, BCGF protein, B cell stimulating factor protein, BSF-1 protein, IL4, IL-4 protein, BCDF protein, IL-4 protein

Poids moléculaire: 13.5 kDa

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation