IL1A Protéine
Aperçu rapide pour IL1A Protéine (ABIN935582)
Antigène
Voir toutes IL1A ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
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Attributs du produit
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Purified recombinant Human IL1 alpha protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent proliferation of Mouse D10S cells is 2 x 10^8 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- IL1A (Interleukin 1 alpha (IL1A))
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Autre désignation
- IL1 alpha
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Sujet
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IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells.
Alternative Names: Leukocyte Endogenous Mediator protein, Lymphocyte-activating factor protein, IL-1 protein, Interleukin 1 alpha protein, MCF protein, Mononuclear Cell Factor protein, IL 1 protein, IL1, IL-1 alpha protein, EP protein, LEM protein, Endogenous Pyrogen protein, Hematopoietin-1 protein, LAF protein, IL-1, IL 1 -
Poids moléculaire
- 17.7 kDa
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Pathways
- Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
Antigène
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