IL1A Protein (AA 113-271) (His tag)

N° du produit ABIN7274874

Détail du produit

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Type de proteíne: Recombinant

Attributs du protein: AA 113-271

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette IL1A protéine est marqué à la His tag.

Fonction: Cynomolgus IL-1 alpha/IL-1A Protein

Séquence: Ser113-Ala271

Attributs du produit: Recombinant Cynomolgus IL-1 alpha/IL-1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser113-Ala271.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL-1 alpha (IL1A Produits)

Synonymes: IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein

Sujet: The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.

Poids moléculaire: 19.23 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.

UniProt: P79340

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints