IL-4 Protéine
Aperçu rapide pour IL-4 Protéine (ABIN935588)
Antigène
Voir toutes IL-4 (IL4) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
-
-
Séquence
- MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
-
Attributs du produit
-
Purified recombinant Rat IL4 protein
Expression System: E.coli
Bioactivity: Tested by its ability to suppress LPS-induced TNF-alpha and MIP-2 production in mouse splenocytes. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
-
-
Vous souhaitez d'autres options pour ce Protein ?
!Découvrez nos protéines personnalisées prédéfinies et nos services de protéines sur mesure !Votre projet nécessite-t-il une personnalisation supplémentaire ? Contactez-nous et découvrez nos solutions protéiques sur mesure
-
Interleukin 4 (IL4) (AA 25-153) protein (His tag)
IL4 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 (IL4) (AA 25-153) protein (His-Avi Tag,Biotin)IL4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 4 (IL4) (AA 23-140) (Active) proteinIL4 Origine: Souris Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 4 (IL4) (AA 25-153) protein (His-Avi Tag)IL4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 4 (IL4) (AA 25-153) (Active) proteinIL4 Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 4 (IL4) (AA 25-153) (Active) protein (His tag,AVI tag,Biotin)IL4 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 4 (IL4) protein (His tag)IL4 Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 4 (IL4) (AA 25-153) (Active) protein (His tag)IL4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 4 (IL4) (AA 63-153) protein (GST tag)IL4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 4 (IL4) (AA 25-153) protein (mFc Tag)IL4 Origine: Humain Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- Supplied as a lyophilized powder.
-
Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
-
Stock
- RT/-20 °C
-
-
- IL-4 (IL4) (Interleukin 4 (IL4))
-
Autre désignation
- IL4
-
Sujet
-
IL4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL4, IL5, IL6, IL10, and IL13, which favor a humoral immune response. Another dominant function of IL4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL4 production by Th2 cells has been associated with elevated IgE production and allergy.
Alternative Names: B cell stimulating factor protein, IL 4, BCDF protein, IL-4, Interleukin 4 protein, BSF-1 protein, IL 4 protein, IL-4 protein, IL4, BCGF protein, IL-4 protein -
Poids moléculaire
- 14.0 kDa
-
Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
Antigène
-
