CCL3 Protéine

N° du produit ABIN935631

Cette protéine Recombinant CCL3 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour CCL3 Protéine (ABIN935631)

Antigène: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 98 % pure

Détail du produit

Séquence: APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA

Attributs du produit: Purified recombinant Human MIP1 alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration of 50.0-100.0 ng/mL.

niveau d'endotoxine: < 0.1 ng per µg (1 EU/µg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

Buffer: Supplied as a lyophilized powder.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Autre désignation: MIP1 alpha

Sujet: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
Alternative Names: MIP-1 alpha protein, LD78 beta protein, MIP 1 alpha, CCL3 protein, MIP 1 alpha protein, MIP-1 alpha protein, MIP-1 alpha, Macrophage Inflammatory Protein-1 alpha protein, MIP1 alpha

Poids moléculaire: 7.8 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy