NOG Protéine
Aperçu rapide pour NOG Protéine (ABIN935694)
Antigène
Voir toutes NOG ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
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Attributs du produit
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Purified recombinant Mouse Noggin protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit 5.0 ng/mL of BMP-4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 1.0-2.0 ng/mL of Noggin. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Noggin (NOG) (AA 20-232) (Active) protein
NOG Origine: Souris Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) (AA 28-232) (Active) proteinNOG Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) protein (His tag)NOG Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (His-IF2DI Tag)NOG Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Noggin (NOG) (AA 28-232) protein (GST tag)NOG Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Noggin (NOG) protein (Fc Tag)NOG Origine: Humain Hôte: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (Fc Tag)NOG Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- NOG (Noggin (NOG))
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Autre désignation
- Noggin
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Sujet
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Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF beta family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF beta ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures.
Alternative Names: NOG protein, SYM1 protein, SYNS1 protein , Synostoses (multiple) syndrome 1 protein, SYNS 1 protein, Symphalangism 1 (proximal) protein, SYM 1 protein -
Poids moléculaire
- 46.4 kDa
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Pathways
- Stem Cell Maintenance, Tube Formation
Antigène
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