IGF1 Protéine

N° du produit ABIN935729

Cette protéine Recombinant IGF1 est produite dans Insect cells (Sf9). Il y a 1 publication disponible.

Aperçu rapide pour IGF1 Protéine (ABIN935729)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Pureté: > 90 % pure

Détail du produit

Séquence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERCGDAVPR R

Attributs du produit: Purified recombinant Human PIGF1 protein
Expression System: Sf-9 insect cells

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted with 50 mM acetic acid or PBS.

Buffer: Lyophilized with carrier-protein (HSA) and can be

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Référence

Ablonczy, Crosson: "VEGF modulation of retinal pigment epithelium resistance." dans: Experimental eye research, Vol. 85, Issue 6, pp. 762-71, (2007) (PubMed).

Détail du antigène

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: IGF1

Sujet: Human Placenta Growth Factor-1 (PlGF-1), a 19 kDa protein consisting of 131 amino acid residues is produced as a homodimer. Human Placenta Growth Factor (PlGF) is a polypeptide growth factor and a member of the platelet-derived growth factor family but more related to vascular endothelial growth factor (VEGF). PlGF-1 acts only as a very weak mitogen for some endothelial cell types and as a potent chemoattractant for monocytes. The physiological function in vivo is still controversal. In several reports it was shown not to be a potent mitogen for endotehlial cells and not angiogenic in vivo by using different assays.
Alternative Names: PGF protein, PIGF-1, PIGF 1, PIGF protein, PIGF 1 protein, PIGF1, Placenta Growth Factor-1 protein, PIGF-1 protein

Poids moléculaire: 19 kDa

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation