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RBP3 Produits

(Retinol Binding Protein 3, Interstitial (RBP3))
Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008].

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Catégories RBP3 en vedette

RBP3 Anticorps

High quality antibodies with extensive validation data.

RBP3 Kits ELISA

Reliable ELISA kits for a wide range of species.

RBP3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RBP3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7444433
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application IHC
Validations
  • (2)
N° du produit ABIN7233795
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN519681
Quantité 50 μL
Fiche technique Fiche technique

RBP3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969936
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962335
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959153
Quantité 96 tests
Fiche technique Fiche technique

RBP3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124850
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317651
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094986
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RBP3

Lee, Taylor: "Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs." dans: Journal of leukocyte biology, Vol. 97, Issue 6, pp. 1101-9, (2015) (PubMed).

Shil, Kwon, Zhu, Verma, Daniell, Li: "Oral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental uveitis and autoimmune uveoretinitis." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 12, pp. 2069-82, (2014) (PubMed).

Lee, Taylor: "Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 8, pp. 4103-11, (2013) (PubMed).

Lee, Taylor: "Following EAU recovery there is an associated MC5r-dependent APC induction of regulatory immunity in the spleen." dans: Investigative ophthalmology & visual science, Vol. 52, Issue 12, pp. 8862-7, (2011) (PubMed).

Hegde, Srinivasula, Ahmad, Fernandes-Alnemri, Alnemri: "Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist." dans: The Journal of biological chemistry, Vol. 273, Issue 14, pp. 7783-6, (1998) (PubMed).

Elangovan, Chinnadurai: "Functional dissection of the pro-apoptotic protein Bik. Heterodimerization with anti-apoptosis proteins is insufficient for induction of cell death." dans: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24494-8, (1997) (PubMed).

Han, Sabbatini, White: "Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K." dans: Molecular and cellular biology, Vol. 16, Issue 10, pp. 5857-64, (1996) (PubMed).

Boyd, Gallo, Elangovan, Houghton, Malstrom, Avery, Ebb, Subramanian, Chittenden, Lutz: "Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins." dans: Oncogene, Vol. 11, Issue 9, pp. 1921-8, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à RBP3

retinol binding protein 3 (rbp3), retinol binding protein 3 (RBP3), interphotoreceptor retinoid-binding protein (glr2547), interphotoreceptor retinoid-binding protein (XOO2681), interphotoreceptor retinoid-binding protein (AMED_0162), interphotoreceptor retinoid-binding protein (ambt_08395), retinol binding protein 3, interstitial (Rbp3), retinol binding protein 3 (Rbp3), D10S64, D10S65, D10S66, Irbp, IRBP, Rbp-3, RBPI, RP66

Protein level used designations for RBP3

  • irbp gene 2
  • retinol-binding protein 3
  • interphotoreceptor retinoid-binding protein
  • retinol binding protein 3, interstitial
  • retinol-binding protein 3-like
  • interstitial retinol-binding protein
  • interphotoreceptor retinoid binding protein
  • interphotoreceptor retinol- binding protein
  • 7S protein
  • IRBP
  • protein 7S
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