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RCC1 Produits

(Regulator of Chromosome Condensation 1 (RCC1))

Catégories

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.

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Catégories RCC1 en vedette

RCC1 Anticorps

High quality antibodies with extensive validation data.

RCC1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RCC1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (13)
N° du produit ABIN6146817
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7262150
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (1)
  • (4)
N° du produit ABIN2855859
Quantité 100 μL
Fiche technique Fiche technique

RCC1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6207329
Quantité 96 tests
Fiche technique Fiche technique

RCC1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317690
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317692
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3086942
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RCC1

Hayes, Duan, Bowen, Kalab, Rothstein: "C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import." dans: eLife, Vol. 9, (2020) (PubMed).

Gillon, Nielsen, Steel, Cornwall, Sheard: "Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health." dans: GeroScience, Vol. 40, Issue 2, pp. 177-192, (2018) (PubMed).

Wang, Xue, Hu, Wei, Zhang, Ge, Liang: "Structure-dependent mitochondrial dysfunction and hypoxia induced with single-walled carbon nanotubes." dans: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 14, pp. 2859-69, (2014) (PubMed).

Li, Zheng: "Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells." dans: Genes & development, Vol. 18, Issue 5, pp. 512-27, (2004) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Cushman, Stenoien, Moore: "The dynamic association of RCC1 with chromatin is modulated by Ran-dependent nuclear transport." dans: Molecular biology of the cell, Vol. 15, Issue 1, pp. 245-55, (2003) (PubMed).

Ciarallo, Subramaniam, Hung, Lee, Kotchetkov, Sandhu, Milic, Slingerland: "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest." dans: Molecular and cellular biology, Vol. 22, Issue 9, pp. 2993-3002, (2002) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." dans: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Bilbao-Cortés, Hetzer, Längst, Becker, Mattaj: "Ran binds to chromatin by two distinct mechanisms." dans: Current biology : CB, Vol. 12, Issue 13, pp. 1151-6, (2002) (PubMed).

Nemergut, Lindsay, Brownawell, Macara: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." dans: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à RCC1

regulator of chromosome condensation 1 (rcc1), regulator of chromosome condensation 1 (RCC1), regulator of chromosome condensation 1 L homeolog (rcc1.L), Regulator of chromosome condensation 1 (Rcc1), N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1), regulator of chromosome condensation 1 S homeolog (rcc1.S), regulator of chromosome condensation 1 (Rcc1), 4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), Chc1, CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, rcc1, RCC1, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114

Protein level used designations for RCC1

  • chromosome condensation 1
  • fj77f08
  • regulator of chromosome condensation
  • regulator of chromosome condensation 1
  • RCC1 protein
  • Bj1-PA
  • Bj1-PB
  • Bj1-PC
  • CG10480-PA
  • CG10480-PB
  • CG10480-PC
  • in excess
  • side-out
  • possible fragment of potential guanine nucleotide exchange factor
  • SNHG3-RCC1 readthrough transcript
  • cell cycle regulatory protein
  • guanine nucleotide-releasing protein
  • chromosome condensation protein 1
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