RBPJ Produits
(Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
Catégories
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011].
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Catégories RBPJ en vedette
RBPJ Anticorps
High quality antibodies with extensive validation data.
RBPJ Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RBPJ recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
N° du produit
ABIN1538823
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC, IP
Validations
- (5)
N° du produit
ABIN2777213
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (5)
N° du produit
ABIN3032451
Quantité
0.4 mL
Fiche technique
Fiche technique
RBPJ recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969858
Quantité
96 tests
Fiche technique
Fiche technique
RBPJ recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317663
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317665
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3133694
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits RBPJ
: "Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells." dans: eLife, Vol. 5, (2016) (PubMed).: "A genetic cell context-dependent role for ZEB1 in lung cancer." dans: Nature communications, Vol. 7, pp. 12231, (2016) (PubMed).
: "Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model." dans: British journal of cancer, Vol. 109, Issue 3, pp. 667-75, (2013) (PubMed).
: "RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13794-807, (2010) (PubMed).
: "A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 ..." dans: Journal of virology, Vol. 79, Issue 14, pp. 8784-92, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à RBPJ
recombination signal binding protein for immunoglobulin kappa J region (RBPJ), recombination signal binding protein for immunoglobulin kappa J region (Rbpj), recombination signal binding protein for immunoglobulin kappa J region S homeolog (rbpj.S), recombination signal binding protein for immunoglobulin kappa J region a (rbpja), recombination signal binding protein for immunoglobulin kappa J region b (rbpjb), AI843960, AOS3, CBF1, csl, IGKJRB, Igkjrb, IGKJRB1, Igkrsbp, ik:tdsubc_1e8, KBF2, RBP-J, RBP-J kappa, rbpj, RBPJK, RBPjk, RBPSUH, Rbpsuh, rbpsuh, Su(H), Su(H)1, Su(H)2, Su(h)A, su(h)B, SUH, XSu(H), xsu(h)1, xx:tdsubc_1e8Protein level used designations for RBPJ
- CBF-1
- H-2K binding factor-2
- RBP-J kappa
- RBP-JK
- immunoglobulin kappa J region recombination signal binding protein 1
- recombining binding protein suppressor of hairless
- renal carcinoma antigen NY-REN-30
- suppressor of hairless homolog
- J kappa-recombination signal-binding protein
- X-Su(H)
- suppressor of hairless protein 1
- suppressor of hairless protein homolog
- recombination signal binding protein for immunoglobulin kappa J region a
- tdsubc_1e8
- suppressor of hairless 2
- recombining binding protein suppressor of hairless-like
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