RCHY1 Produits
(Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
Catégories
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011].
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Catégories RCHY1 en vedette
RCHY1 Anticorps
High quality antibodies with extensive validation data.
RCHY1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
RCHY1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (4)
N° du produit
ABIN1724723
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7168232
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7251838
Quantité
200 μL
Fiche technique
Fiche technique
RCHY1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6234455
Quantité
96 tests
Fiche technique
Fiche technique
RCHY1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317696
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317698
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3075776
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits RCHY1
: "p27kip1 Expression in non-small cell lung cancer is not an independent prognostic factor." dans: Anticancer research, Vol. 30, Issue 9, pp. 3699-704, (2010) (PubMed).: "The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis." dans: Cell death and differentiation, Vol. 16, Issue 6, pp. 826-37, (2009) (PubMed).
: "Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains." dans: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 21955-70, (2009) (PubMed).
: "Molecular basis of Pirh2-mediated p53 ubiquitylation." dans: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1334-42, (2008) (PubMed).
: "Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53." dans: The EMBO journal, Vol. 26, Issue 13, pp. 3062-74, (2007) (PubMed).
: "Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells." dans: Experimental cell research, Vol. 312, Issue 17, pp. 3370-8, (2006) (PubMed).
: "Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists." dans: Cancer research, Vol. 66, Issue 24, pp. 11817-24, (2006) (PubMed).
: "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3." dans: The EMBO journal, Vol. 24, Issue 9, pp. 1739-49, (2005) (PubMed).
: "Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer." dans: Journal of the National Cancer Institute, Vol. 96, Issue 22, pp. 1718-21, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à RCHY1
ring finger and CHY zinc finger domain containing 1 (RCHY1), ring finger and CHY zinc finger domain containing 1 (Rchy1), ring finger and CHY zinc finger domain containing 1 (rchy1), ring finger and CHY zinc finger domain containing 1 L homeolog (rchy1.L), ARNIP, arnip, CHIMP, chimp, harnip, PIRH2, Pirh2, pirh2, PRO1996, pro1996, RCHY1, RNF199, rnf199, wu:fb37e07, Zfp363, zgc:101128, ZNF363, Znf363, znf363Protein level used designations for RCHY1
- CH-rich interacting match with PLAG1
- E3 ubiquitin-protein ligase Pirh2
- RING finger and CHY zinc finger domain-containing protein 1
- RING finger protein 199
- androgen-receptor N-terminal-interacting protein
- p53-induced protein with a RING-H2 domain
- zinc finger protein 363
- CH-rich-interacting match with PLAG1
- androgen receptor N-terminal-interacting protein
- ring finger and CHY zinc finger domain containing 1
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