Retinoblastoma 1 Produits
(Retinoblastoma 1 (RB1))
Catégories
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008].
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Catégories Retinoblastoma 1 en vedette
Retinoblastoma 1 Anticorps
High quality antibodies with extensive validation data.
Retinoblastoma 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Retinoblastoma 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Retinoblastoma 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validations
- (1)
- (1)
N° du produit
ABIN675294
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
N° du produit
ABIN712946
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN652516
Quantité
400 μL
Fiche technique
Fiche technique
Retinoblastoma 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6574260
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN5526749
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969918
Quantité
96 tests
Fiche technique
Fiche technique
Retinoblastoma 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1317543
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3094954
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3132938
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Retinoblastoma 1
: "IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells." dans: Molecular medicine reports, Vol. 16, Issue 2, pp. 1445-1450, (2018) (PubMed).: "EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop." dans: Nature communications, Vol. 8, Issue 1, pp. 877, (2018) (PubMed).
: "ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells." dans: Nanoscale research letters, Vol. 12, Issue 1, pp. 322, (2017) (PubMed).
: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." dans: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).
: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." dans: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).
: "A Point Mutation in DNA Polymerase β (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer." dans: Journal of Cancer, Vol. 7, Issue 11, pp. 1472-80, (2016) (PubMed).
: "Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus." dans: The international journal of biochemistry & cell biology, Vol. 65, pp. 104-12, (2016) (PubMed).
: "Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response." dans: Journal of proteome research, Vol. 14, Issue 12, pp. 5157-68, (2016) (PubMed).
: "Molecular Determinants for the Inactivation of the Retinoblastoma Tumor Suppressor by the Viral Cyclin-dependent Kinase UL97." dans: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19666-80, (2015) (PubMed).
: "MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes." dans: Cell communication and signaling : CCS, Vol. 12, pp. 66, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à Retinoblastoma 1
RB transcriptional corepressor 1 (RB1), RB transcriptional corepressor like 1 (RBL1), RB transcriptional corepressor 1 (Rb1), RB transcriptional corepressor 1 (rb1), retinoblastoma 1 (rb1), OSRC, p105-Rb, P105-RB, pp110, PP110, pRb, RB, Rb, Rb-1, RB11, zgc:154147Protein level used designations for Retinoblastoma 1
- retinoblastoma suspectibility protein
- retinoblastoma-associated protein
- retinoblastoma-like protein 1
- pp105
- Retinoblastoma 1 (including osteosarcoma)
- pRb
- rb
- retinoblastoma 1 (including osteosarcoma)
- retinoblastoma protein
- retinoblastoma, susceptibility
- Retinoblastoma-associated protein
- retinoblastoma 1
- retinoblastoma-associated protein-like
- spc
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