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RYK Produits

(RYK Receptor-Like Tyrosine Kinase (RYK))
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].

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Catégories RYK en vedette

RYK Anticorps

High quality antibodies with extensive validation data.

RYK Kits ELISA

Reliable ELISA kits for a wide range of species.

RYK Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RYK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
  • (7)
N° du produit ABIN392050
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7174060
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
N° du produit ABIN392051
Quantité 400 μL
Fiche technique Fiche technique

RYK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN4886279
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884386
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730510
Quantité 96 tests
Fiche technique Fiche technique

RYK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319036
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3121366
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3087682
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RYK

Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." dans: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." dans: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." dans: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." dans: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).

Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à RYK

receptor-like tyrosine kinase (RYK), receptor-like tyrosine kinase (ryk), receptor-like tyrosine kinase S homeolog (ryk.S), tyrosine-protein kinase RYK (LOC100541106), receptor-like tyrosine kinase (Ryk), AW536699, d3s3195, D3S3195, ERK-3, jtk5, JTK5, jtk5a, JTK5A, MGC114645, RYK, ryk1, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381

Protein level used designations for RYK

  • RYK receptor-like tyrosine kinase
  • tyrosine kinase RYK
  • ryk receptor-like tyrosine kinase
  • receptor-like tyrosine kinase
  • tyrosine-protein kinase RYK
  • tyrosine kinase-related protein
  • tyrosine-protein kinase RYK-like
  • JTK5A protein tyrosine kinase
  • hydroxyaryl-protein kinase
  • NYK-R
  • growth factor receptor
  • kinase VIK
  • met-related kinase
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