Recombinant Souris anti-Humain Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Anticorps

N° du produit ABIN7879476

Aperçu rapide pour Recombinant Souris anti-Humain Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Anticorps (ABIN7879476)

Antigène: Igk (Immunoglobulin kappa Chain Complex (Igk))

Type d'anticorp: Recombinant Antibody

Clonalité: Monoclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RL1C1

Isotype: IgG1, kappa

Détail du produit

Épitope: Light Chain

Reactivité: Humain

Hôte: Souris

Fonction: Recombinant Kappa Light Chain Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human Ig kappa chain was used as the immunogen for this recombinant Kappa Light Chain antibody.

Information d'application

Indications d'application: The optimal dilution of the recombinant Kappa Light Chain antibody for each application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Kappa Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détail du antigène

Antigène: Igk (Immunoglobulin kappa Chain Complex (Igk))

Autre désignation: Kappa

Sujet: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01601