Souris anti-Humain Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Anticorps (CF®488A)

N° du produit ABIN7879479

Aperçu rapide pour Souris anti-Humain Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Anticorps (CF®488A) (ABIN7879479)

Antigène: Igk (Immunoglobulin kappa Chain Complex (Igk))

Clonalité: Monoclonal

Conjugué: CF®488A

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KLC709

Isotype: IgG1, kappa

Détail du produit

Épitope: Light Chain

Reactivité: Humain

Hôte: Souris

Fonction: Kappa Light Chain Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human Kappa light chain was used as the immunogen for this Kappa light chain antibody.

Information d'application

Indications d'application: Optimal dilution of the Kappa Light Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the Kappa Light Chain antibody at 2-8oC, protected from light.

Détail du antigène

Antigène: Igk (Immunoglobulin kappa Chain Complex (Igk))

Autre désignation: Kappa

Sujet: This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.