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SIGLEC5 Produits

(Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012].

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Catégories SIGLEC5 en vedette

SIGLEC5 Anticorps

High quality antibodies with extensive validation data.

SIGLEC5 Kits ELISA

Reliable ELISA kits for a wide range of species.

SIGLEC5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SIGLEC5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
N° du produit ABIN7193301
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7249022
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN544592
Quantité 400 μL
Fiche technique Fiche technique

SIGLEC5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN625088
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5526846
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5510738
Quantité 96 tests
Fiche technique Fiche technique

SIGLEC5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275598
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275589
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275613
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SIGLEC5

Suematsu, Miyamoto, Saijo, Yamasaki, Tada, Yoshida, Miyake: "Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses." dans: The Journal of biological chemistry, Vol. 294, Issue 45, pp. 16776-16788, (2019) (PubMed).

Huang, Low, Wang, Hsu, Angata: "Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses." dans: The Journal of biological chemistry, Vol. 293, Issue 51, pp. 19645-19658, (2018) (PubMed).

Alkhodair, Almhanna, McGetrick, Gedair, Gallagher, Fernandez-Fuertes, Tharmalingam, Larsen, Fitzpatrick, Lonergan, Evans, Carrington, Reid: "Siglec expression on the surface of human, bull and ram sperm." dans: Reproduction (Cambridge, England), Vol. 155, Issue 4, pp. 361-371, (2018) (PubMed).

Wu, Ding, Han, Arriens, Wei, Han, Pedroza, Jiang, Anolik, Petri, Sanz, Saxena, Mohan: "Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study." dans: Journal of proteome research, Vol. 15, Issue 7, pp. 2102-14, (2016) (PubMed).

Madge, Maggioni, Pascolutti, Amin, Waespy, Bellette, Thomson, Kelm, von Itzstein, Haselhorst: "Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy." dans: Scientific reports, Vol. 6, pp. 36012, (2016) (PubMed).

Pepin, Mezouar, Pegon, Muczynski, Adam, Bianchini, Bazaa, Proulle, Rupin, Paysant, Panicot-Dubois, Christophe, Dubois, Lenting, Denis: "Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity." dans: Scientific reports, Vol. 6, pp. 37953, (2016) (PubMed).

Ali, Fong, Carlin, Busch, Linden, Angata, Areschoug, Parast, Varki, Murray, Nizet, Varki: "Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus." dans: The Journal of experimental medicine, Vol. 211, Issue 6, pp. 1231-42, (2014) (PubMed).

Yang, Jiang, Li, Qiu, Zhang, Carter, Al-Quran, Li: "Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery." dans: Journal of hematology & oncology, Vol. 7, pp. 5, (2014) (PubMed).

Izquierdo-Useros, Lorizate, Puertas, Rodriguez-Plata, Zangger, Erikson, Pino, Erkizia, Glass, Clotet, Keppler, Telenti, Kräusslich, Martinez-Picado: "Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides." dans: PLoS biology, Vol. 10, Issue 12, pp. e1001448, (2012) (PubMed).

Zou, Chastain, Moir, Ford, Trandem, Martinelli, Cicala, Crocker, Arthos, Sun: "Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids." dans: PLoS ONE, Vol. 6, Issue 9, pp. e24559, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à SIGLEC5

sialic acid binding Ig like lectin 5 (SIGLEC5), sialic acid-binding Ig-like lectin 5 (LOC100597560), sialic acid binding Ig-like lectin 5 (Siglec5), CD33L2, CD170, OB-BP2, OBBP2, SIGLEC-5

Protein level used designations for SIGLEC5

  • CD33 antigen-like 2
  • OB-binding protein 2
  • obesity-binding protein 2
  • sialic acid-binding Ig-like lectin 5
  • sialic acid-binding immunoglobulin-like lectin 5
  • sialic acid binding Ig-like lectin 5
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