SLC7A5 Produits
(Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
Catégories
Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L- leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.
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Catégories SLC7A5 en vedette
SLC7A5 Anticorps
High quality antibodies with extensive validation data.
SLC7A5 Kits ELISA
Reliable ELISA kits for a wide range of species.
SLC7A5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC7A5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC (p), IF (cc)
Validations
- (2)
- (3)
N° du produit
ABIN1387470
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (3)
N° du produit
ABIN1682793
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN6243100
Quantité
200 μL
Fiche technique
Fiche technique
SLC7A5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959624
Quantité
96 tests
Fiche technique
Fiche technique
SLC7A5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7406977
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3114267
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3137587
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SLC7A5
: "Significant relationship between the LAT1 expression pattern and chemoresistance in ovarian clear cell carcinoma." dans: Virchows Archiv : an international journal of pathology, (2019) (PubMed).: "Possible Molecular Mechanisms by Which an Essential Oil Blend from Star Anise, Rosemary, Thyme, and Oregano and Saponins Increase the Performance and Ileal Protein Digestibility of Growing Broilers." dans: Journal of agricultural and food chemistry, Vol. 65, Issue 32, pp. 6821-6830, (2017) (PubMed).
: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." dans: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).
: "Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults." dans: The American journal of clinical nutrition, Vol. 104, Issue 4, pp. 1014-1022, (2016) (PubMed).
: "Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers." dans: Science (New York, N.Y.), Vol. 353, Issue 6304, pp. 1161-5, (2016) (PubMed).
: "High expression of CD98 alters epithelial barrier functions to promote induction of airway allergy." dans: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 42, Issue 7, pp. 1051-9, (2012) (PubMed).
: "Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human L-type amino-acid transporter 1." dans: Cancer science, Vol. 99, Issue 5, pp. 1000-7, (2008) (PubMed).
: "Transcriptional regulation of the LAT-1/CD98 light chain." dans: Biochemical and biophysical research communications, Vol. 318, Issue 2, pp. 529-34, (2004) (PubMed).
: "Expression of a system L neutral amino acid transporter at the blood-brain barrier." dans: Neuroreport, Vol. 11, Issue 16, pp. 3507-11, (2001) (PubMed).
: "Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines." dans: Biochimica et biophysica acta, Vol. 1514, Issue 2, pp. 291-302, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à SLC7A5
solute carrier family 7 member 5 (SLC7A5), solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (Slc7a5), solute carrier family 7 (amino acid transporter light chain, L system), member 5 (SLC7A5), solute carrier family 7 member 5 (Slc7a5), solute carrier family 7 member 5 S homeolog (slc7a5.S), solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (Slc3a2), 4F2, 4F2HC, 4F2LC, AI314110, CD98, Cd98, D0H16S474E, D16S469E, E16, hLAT1, JHI-21, LAT-1, LAT1, Ly-10, Ly-m10, Ly10, Mdu1, Mgp-2hc, MPE16, NACAE, SLC7A5, slc7a5a, TA1Protein level used designations for SLC7A5
- 4F2 LC
- 4F2 light chain
- CD98 light chain
- L-type amino acid transporter 1
- integral membrane protein E16
- large neutral amino acids transporter 1
- large neutral amino acids transporter small subunit 1
- sodium-independent neutral amino acid transporter LAT1
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
- solute carrier family 7 member 5
- y+ system cationic amino acid transporter
- 4F2LC
- LAT1 light chain
- blood-brain barrier large neutral amino acid transporter light chain
- tumor-associated protein 1
- L amino acid transporter-1
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 a
- large neutral amino acids transporter small subunit 1-like
- 4F2 cell-surface antigen heavy chain
- CD98 antigen
- CD98 heavy chain
- antigen identified by monoclonal antibodies 4F2
- type II transmembrane protein
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