SLC7A8 Produits
(Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
Catégories
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).
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Catégories SLC7A8 en vedette
SLC7A8 Anticorps
High quality antibodies with extensive validation data.
SLC7A8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SLC7A8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC, IHC (p), IF, IP
Validations
- (5)
N° du produit
ABIN1500960
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (2)
N° du produit
ABIN6243302
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN525163
Quantité
100 μg
Fiche technique
Fiche technique
SLC7A8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320534
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1320533
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3118920
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SLC7A8
: "Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources." dans: Genes & nutrition, Vol. 16, Issue 1, pp. 14, (2021) (PubMed).: "Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma." dans: Brain tumor pathology, Vol. 34, Issue 4, pp. 179-181, (2018) (PubMed).
: "Methylmercury Uptake into BeWo Cells Depends on LAT2-4F2hc, a System L Amino Acid Transporter." dans: International journal of molecular sciences, Vol. 18, Issue 8, (2018) (PubMed).
: "Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic." dans: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 1, pp. 129-137, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à SLC7A8
solute carrier family 7 member 8 (SLC7A8), solute carrier family 7 member 8 (Slc7a8), solute carrier family 7 member 8 L homeolog (slc7a8.L), solute carrier family 7 member 8 (slc7a8), solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8), solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8), solute carrier family 7 (amino acid transporter light chain, L system), member 8b (slc7a8b), 4F2LC-5, AA408822, LAT2, Lat2, lat2, Lat4, LPI-PC1, lpi-pc1, si:ch211-14a17.3, si:zc14a17.3, slc7a8, XAA2Protein level used designations for SLC7A8
- L-type amino acid transporter 2
- integral membrane protein E16H
- large neutral amino acids transporter small subunit 2
- solute carrier family 7 (amino acid transporter, L-type), member 8
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
- cationic amino acid transporter y+ system
- solute carrier family 7 member 8
- glycoprotein-associated amino acid transporter LAT2
- 4F2-LC5
- mLAT2
- solute carrier family 8 (cationic amino acid transporter, y+ system), member 7
- solute carrier family 7 (amino acid transporter light chain, L system), member 8
- zmp:0000000645
- zmp:0000000781
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