anticorps LAT2, anticorps LPI-PC1, anticorps Lat2, anticorps Lat4, anticorps XAA2, anticorps lat2, anticorps lpi-pc1, anticorps 4F2LC-5, anticorps AA408822, anticorps si:ch211-14a17.3, anticorps si:zc14a17.3, anticorps slc7a8, anticorps solute carrier family 7 member 8, anticorps solute carrier family 7 member 8 L homeolog, anticorps solute carrier family 7 (amino acid transporter, L-type), member 8, anticorps solute carrier family 7 (cationic amino acid transporter, y+ system), member 8, anticorps solute carrier family 7 (amino acid transporter light chain, L system), member 8b, anticorps SLC7A8, anticorps Slc7a8, anticorps slc7a8.L, anticorps slc7a8, anticorps slc7a8b
Sujet
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.