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SPINK1 Produits

(serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))

Catégories

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008].

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Catégories SPINK1 en vedette

SPINK1 Anticorps

High quality antibodies with extensive validation data.

SPINK1 Kits ELISA

Reliable ELISA kits for a wide range of species.

SPINK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SPINK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IP
Validations
  • (8)
  • (5)
N° du produit ABIN562978
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (3)
N° du produit ABIN7436420
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7168925
Quantité 100 μg
Fiche technique Fiche technique

SPINK1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6959380
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962684
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970111
Quantité 96 tests
Fiche technique Fiche technique

SPINK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125036
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321179
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1321181
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SPINK1

Hellmann, Paiella, Kostro, Marek, Adrych, Śledziński, Hać, Bassi: "Surgical decompression of Wirsung duct reduces serum concentration of SPINK1 in patients with chronic pancreatitis." dans: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 18, Issue 3, pp. 275-279, (2018) (PubMed).

Mehner, Oberg, Kalli, Nassar, Hockla, Pendlebury, Cichon, Goergen, Maurer, Goode, Keeney, Jatoi, Sahin-Tóth, Copland, Radisky, Radisky: "Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers." dans: Oncotarget, Vol. 6, Issue 34, pp. 35737-54, (2016) (PubMed).

Palanisamy, Tsodikov, Yan, Suleman, Rittmaster, Lucia, Chinnaiyan, Fleshner, Kunju: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." dans: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).

Ateeq, Kunju, Carskadon, Pandey, Singh, Pradeep, Tandon, Singhai, Goel, Amit, Agarwal, Dinda, Seth, Tsodikov, Chinnaiyan, Palanisamy: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." dans: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).

Zhang, Wang, Hu, Wang, Yu, Wang: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." dans: Tumour biology, (2015) (PubMed).

El-mezayen, Metwally, Darwish: "A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer." dans: Tumour biology, Vol. 35, Issue 3, pp. 2759-67, (2014) (PubMed).

Smith, Palanisamy, Zuhlke, Johnson, Siddiqui, Chinnaiyan, Kunju, Cooney, Tomlins: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." dans: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).

Wang, Wang, Su, Lu, Song, Yang, Fu, Tan, Han: "Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer." dans: The Prostate, Vol. 74, Issue 7, pp. 689-701, (2014) (PubMed).

Rink, Park, Volkmer, Xylinas, Hansen, Cha, Robinson, Hautmann, Küfer, Engel, Chun, Dahlem, Rubin, Shariat, Mosquera: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." dans: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).

Bhalla, Kunju, Tomlins, Christopherson, Cortez, Carskadon, Siddiqui, Park, Mosquera, Pestano, Rubin, Chinnaiyan, Palanisamy: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à SPINK1

serine peptidase inhibitor, Kazal type 1 (SPINK1), serine peptidase inhibitor, Kazal type 1 (Spink1), p12, PCTT, PSTI, Psti, SPINK1, Spink3, TATI, TCP

Protein level used designations for SPINK1

  • pancreatic secretory trypsin inhibitor
  • serine protease inhibitor Kazal-type 1
  • serine protease inhibitor, Kazal type 1
  • tumor-associated trypsin inhibitor
  • PSTI-II
  • calcium transport inhibitor
  • caltrin
  • pancreatic secretory trypsin inhibitor II
  • pancreatic secretory trypsin inhibitor type II (PSTI-II)
  • serine peptidase inhibitor, Kazal type 3
  • serine protease inhibitor Kazal-type 3
  • serine protease inhibitor, Kazal type 3
  • serine peptidase inhibitor, Kazal type 1
  • prostatic secretory glycoprotein
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