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SPTLC3 Protéines

(Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3))

The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT\; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].

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SPTLC3 Protein (AA 1-552) (His tag)

custom-made SPTLC3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant SPTLC3 Protein, UniprotID Q9NUV7

3 images

N° du produit ABIN7555611

Détails

SPTLC3 Protein (AA 1-563) (His tag)

custom-made SPTLC3 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Sptlc3 Protein, UniprotID Q8BG54

3 images

N° du produit ABIN7558527

Détails

SPTLC3 Protein (AA 238-552) (His tag)

SPTLC3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

N° du produit ABIN7408891

Détails

SPTLC3 Protein (AA 80-563) (His tag)

SPTLC3 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % SDS, WB, Imm, PC

N° du produit ABIN7408894

Détails

SPTLC3 Protein (AA 1-563) (Strep Tag)

custom-made SPTLC3 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3124635

Détails

SPTLC3 Protein (AA 1-552) (Strep Tag)

custom-made SPTLC3 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3118538