STAT6 Produits
(Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
Catégories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Catégories STAT6 en vedette
STAT6 Anticorps
High quality antibodies with extensive validation data.
STAT6 Kits ELISA
Reliable ELISA kits for a wide range of species.
STAT6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
STAT6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
N° du produit
ABIN563038
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IP, IF, ICC
Validations
- (5)
N° du produit
ABIN6255720
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (5)
N° du produit
ABIN6148581
Quantité
100 μL
Fiche technique
Fiche technique
STAT6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (1)
- (5)
N° du produit
ABIN1981845
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN1981731
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN4889794
Quantité
96 tests
Fiche technique
Fiche technique
STAT6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125097
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125096
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321608
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits STAT6
: "Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major." dans: Frontiers in immunology, Vol. 9, pp. 1, (2019) (PubMed).: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice." dans: The Journal of experimental medicine, Vol. 215, Issue 8, pp. 2175-2195, (2018) (PubMed).
: "Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1." dans: The Journal of pharmacology and experimental therapeutics, Vol. 360, Issue 3, pp. 435-444, (2017) (PubMed).
: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." dans: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).
: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." dans: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).
: "Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity." dans: Journal of radiation research, Vol. 57, Issue 2, pp. 133-41, (2017) (PubMed).
: "IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1744-52, (2015) (PubMed).
: "STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression." dans: Journal of hepato-biliary-pancreatic sciences, Vol. 21, Issue 10, pp. 767-76, (2014) (PubMed).
: "The role of STAT-6 as a key transcription regulator in HeLa cell death induced by IFN-?/TNF-? co-immobilized on nanoparticles." dans: Biomaterials, Vol. 35, Issue 18, pp. 5016-27, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à STAT6
signal transducer and activator of transcription 6 (STAT6), signal transducer and activator of transcription 6 (Stat6), signal transducer and activator of transcription 6-like (LOC100859543), D12S1644, IL-4-STAT, STAT6B, STAT6CProtein level used designations for STAT6
- signal transducer and transcription activator 6
- STAT, interleukin4-induced
- signal transducer and activator of transcription 6
- transcription factor IL-4 STAT
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