Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Produits
(Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
Catégories
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008].
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Catégories Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) en vedette
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Anticorps
High quality antibodies with extensive validation data.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Kits ELISA
Reliable ELISA kits for a wide range of species.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
N° du produit
ABIN520465
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN7270595
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Pig, Rabbit
Application
WB, IHC
Validations
- (1)
- (3)
N° du produit
ABIN2781788
Quantité
100 μL
Fiche technique
Fiche technique
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6959725
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962626
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959723
Quantité
96 tests
Fiche technique
Fiche technique
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1321302
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3097340
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3128113
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
: "TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model." dans: Neuropharmacology, Vol. 111, pp. 142-159, (2016) (PubMed).: "The role of 5α-reductase type 1 associated with intratumoral dihydrotestosterone concentrations in human endometrial carcinoma." dans: Molecular and cellular endocrinology, Vol. 401, pp. 56-64, (2015) (PubMed).
: "Hamster SRD5A3 lacks steroid 5α-reductase activity in vitro." dans: Steroids, Vol. 94, pp. 41-50, (2015) (PubMed).
: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." dans: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
: "Resistance training restores muscle sex steroid hormone steroidogenesis in older men." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 4, pp. 1891-7, (2014) (PubMed).
: "Seoritae extract reduces prostate weight and suppresses prostate cell proliferation in a rat model of benign prostate hyperplasia." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 475876, (2014) (PubMed).
: "46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5α-reductase type-2 (SRD5A2) gene." dans: Molecular genetics & genomic medicine, Vol. 2, Issue 4, pp. 292-6, (2014) (PubMed).
: "DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats." dans: Calcified tissue international, Vol. 89, Issue 2, pp. 105-10, (2011) (PubMed).
: "Molecular analysis of the SRD5A2 in 46,XY subjects with incomplete virilization: the P212R substitution of the steroid 5alpha-reductase 2 may constitute an ancestral founder mutation in Mexican ..." dans: Journal of andrology, Vol. 31, Issue 4, pp. 358-64, (2010) (PubMed).
: "VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 10, pp. 3223-9, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
steroid 5 alpha-reductase 2 (SRD5A2), steroid 5 alpha-reductase 2 (Srd5a2), steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2), 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (LOC100125532), steroid-5-alpha-reductase, alpha polypeptide 2a (srd5a2a), steroid-5-alpha-reductase, alpha polypeptide 2b (srd5a2b), 5ART2, CH73-233A22.6, S5AR 2, SRD5A2, Srd5a2, SRD5alpha2, wu:fk70d02, zgc:109942, zgc:112208, zgc:112455Protein level used designations for Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 5 alpha-SR2
- S5AR 2
- SR type 2
- steroid 5-alpha-reductase 2
- type II 5-alpha reductase
- steroid 5 alpha reductase type2
- prostatic steroid 5-alpha-reductase type II
- steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- steroid-5-alpha-reductase alpha polypeptide 2
- steroid-5-alpha-reductase, alpha polypeptide 2b
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