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STEAP4 Produits

(STEAP Family Member 4 (STEAP4))

Catégories

The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011].

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Catégories STEAP4 en vedette

STEAP4 Anticorps

High quality antibodies with extensive validation data.

STEAP4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

STEAP4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
N° du produit ABIN7192673
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN7270588
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, WB, IF, ICC
Validations
  • (2)
N° du produit ABIN6265335
Quantité 100 μL
Fiche technique Fiche technique

STEAP4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6207671
Quantité 96 tests
Fiche technique Fiche technique

STEAP4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3127741
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3115570
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5853589
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits STEAP4

Xue, Bredell, Anderson, Martin, Mays, Nagao-Kitamoto, Huang, Győrffy, Greenson, Hardiman, Spence, Kamada, Shah: "Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 45, pp. E9608-E9617, (2018) (PubMed).

Chuang, Guh, Lu, Wang, Chen, Chuang: "Steap4 attenuates high glucose and S100B-induced effects in mesangial cells." dans: Journal of cellular and molecular medicine, Vol. 19, Issue 6, pp. 1234-44, (2015) (PubMed).

Wellen, Fucho, Gregor, Furuhashi, Morgan, Lindstad, Vaillancourt, Gorgun, Saatcioglu, Hotamisligil: "Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis." dans: Cell, Vol. 129, Issue 3, pp. 537-48, (2007) (PubMed).

Ohgami, Campagna, McDonald, Fleming: "The Steap proteins are metalloreductases." dans: Blood, Vol. 108, Issue 4, pp. 1388-94, (2006) (PubMed).

Korkmaz, Korkmaz, Kurys, Elbi, Wang, Klokk, Hammarstrom, Troen, Svindland, Hager, Saatcioglu: "Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer." dans: Oncogene, Vol. 24, Issue 31, pp. 4934-45, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à STEAP4

STEAP4 metalloreductase (STEAP4), STEAP4 metalloreductase L homeolog (steap4.L), STEAP4 metalloreductase (Steap4), STEAP4 metalloreductase (steap4), metalloreductase STEAP4 (LOC100136336), metalloreductase STEAP4 (LOC100353852), STEAP family member 4 (Steap4), STEAP family member 4 (steap4), 1110021O17Rik, AI481214, MGC68826, MGC108044, si:dkey-53p21.1, STAMP2, STEAP4, steap4, TIARP, Tiarp, TNFAIP9, Tnfaip9, zgc:112143

Protein level used designations for STEAP4

  • metalloreductase STEAP4
  • six transmembrane prostate protein 2
  • six-transmembrane epithelial antigen of prostate 4
  • sixTransMembrane protein of prostate 2
  • tumor necrosis factor, alpha-induced protein 9
  • tumor necrosis-alpha-induced adipose-related protein
  • STEAP family member 4
  • Ab1-219
  • six transmembrane epithelial antigen of the prostate 4
  • metalloreductase STEAP4-like
  • Tnfa-induced adipose-related protein
  • dudulin 4
  • dudulin-4
  • tumor necrosis factor-alpha-induced adipose-related protein
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