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TAP2 Produits

(Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].

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Catégories TAP2 en vedette

TAP2 Anticorps

High quality antibodies with extensive validation data.

TAP2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TAP2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TAP2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN3022237
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
  • (3)
N° du produit ABIN680123
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN6243497
Quantité 200 μL
Fiche technique Fiche technique

TAP2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1122075
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1122077
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1122076
Quantité 96 tests
Fiche technique Fiche technique

TAP2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322144
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3095846
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3133904
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TAP2

Feigenberg, Clarke, Virtanen, Plotkin, Letarte, Rosen, Bernardini, Kollara, Brown, Murphy: "Molecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites." dans: BioMed research international, Vol. 2014, pp. 367103, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Tang, Freedman, Allen, Karita, Musonda, Braga, Jamieson, Louie, Kaslow: "Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans." dans: Genes and immunity, Vol. 2, Issue 1, pp. 32-40, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à TAP2

transporter 2, ATP binding cassette subfamily B member (TAP2), transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2), transporter 2, ATP binding cassette subfamily B member (Tap2), ABC18, ABCB3, Abcb3, AI462429, APT2, Cim, D6S217E, Ham-2, Ham2, jas, MTP2, PSF-2, PSF2, RING11, Tap-2, Y1

Protein level used designations for TAP2

  • ABC transporter, MHC 2
  • ATP-binding cassette, sub-family B (MDR/TAP), member 3
  • antigen peptide transporter 2
  • peptide supply factor 2
  • peptide transporter PSF2
  • peptide transporter involved in antigen processing 2
  • really interesting new gene 11 protein
  • transporter 2, ABC (ATP binding cassette)
  • ATP dependent transport protein family member
  • ATP-binding cassette sub-family B member 3
  • histocompatibility antigen modifier 2
  • APT2
  • Transporter 2 ABC (ATP binding cassette)
  • ABC-transporter
  • transporter 2, ABC(ATP binding cassette)
  • transporter 2, ATP-binding cassette, sub-family B
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