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TET2 Produits

(Tet Methylcytosine Dioxygenase 2 (TET2))

Catégories

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

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Catégories TET2 en vedette

TET2 Anticorps

High quality antibodies with extensive validation data.

TET2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TET2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (6)
N° du produit ABIN6149017
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
N° du produit ABIN7193624
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (5)
N° du produit ABIN7261632
Quantité 200 μL
Fiche technique Fiche technique

TET2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970599
Quantité 96 tests
Fiche technique Fiche technique

TET2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7535260
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7535933
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
N° du produit ABIN7535088
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TET2

Lei, Wu, Gu, Ji, Yang: "Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats." dans: Frontiers in neuroscience, Vol. 14, pp. 573107, (2020) (PubMed).

Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." dans: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).

Tucker, Getchell, McCarthy, Ohman, Sasamoto, Xu, Ko, Gupta, Shafrir, Medina, Lee, MacDonald, Malik, Hasselblatt, Li, Zhang, Kaplan, Murphy, Hirsch, Liu, Matulonis, Terry, Lian, Dinulescu: "Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 6, pp. 1389-1401, (2018) (PubMed).

Fischer, Miles: "Silencing HIF-1α induces TET2 expression and augments ascorbic acid induced 5-hydroxymethylation of DNA in human metastatic melanoma cells." dans: Biochemical and biophysical research communications, Vol. 490, Issue 2, pp. 176-181, (2017) (PubMed).

Wallner, Schröder, Leitão, Berulava, Haak, Beißer, Rahmann, Richter, Manke, Bönisch, Arrigoni, Fröhler, Klironomos, Chen, Rajewsky, Müller, Ebert, Lengauer, Barann, Rosenstiel, Gasparoni, Nordström et al.: "Epigenetic dynamics of monocyte-to-macrophage differentiation. ..." dans: Epigenetics & chromatin, Vol. 9, pp. 33, (2016) (PubMed).

Gong, Guo, Niu, Jin, Zhang, Shi, Zhang, Li, Chen, Ma: "Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma." dans: Oncotarget, Vol. 8, Issue 1, pp. 315-328, (2016) (PubMed).

Tsai, Li, Chen, Yeh, Huang, Tseng, Fu, Liou, Pan, Huang, Chen, Chang, Ger, Chang: "Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype." dans: Breast cancer research and treatment, Vol. 153, Issue 1, pp. 219-34, (2015) (PubMed).

Orr, Haffner, Nelson, Yegnasubramanian, Eberhart: "Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma." dans: PLoS ONE, Vol. 7, Issue 7, pp. e41036, (2012) (PubMed).

Langemeijer, Kuiper, Berends, Knops, Aslanyan, Massop, Stevens-Linders, van Hoogen, van Kessel, Raymakers, Kamping, Verhoef, Verburgh, Hagemeijer, Vandenberghe, de Witte, van der Reijden, Jansen: "Acquired mutations in TET2 are common in myelodysplastic syndromes." dans: Nature genetics, Vol. 41, Issue 7, pp. 838-42, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à TET2

tet methylcytosine dioxygenase 2 (TET2), tet methylcytosine dioxygenase 2 (Tet2), Ayu17-449, E130014J05Rik, KIAA1546, MDS, mKIAA1546, RGD1311625

Protein level used designations for TET2

  • methylcytosine dioxygenase TET2
  • probable methylcytosine dioxygenase TET2
  • tet oncogene family member 2
  • tet oncogene 2
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